Photobiomodulation mitigates Bothrops jararacussu venom-induced damage in myoblast cells by enhancing myogenic factors and reducing cytokine production

Gonçalves Silva, Luciana Miato; Almeida Gouveia, Viviane; Russo Soeiro Campos, Gabriela; Squarzone Dale, Camila; da Palma, Renata Kelly; Ligeiro de Oliveira, Ana Paula; Labat Marcos, Rodrigo; Cosme Gutierrez Duran, Cinthya; Cogo, José Carlos; Silva Junior, José Antonio; Zamuner, Stella Regina

Publication date

2024

URI http://hdl.handle.net/10854/180238

DOI

https://doi.org/10.1371/journal.pntd.0012227

ISSN

1935-2735

Abstract

Photobiomodulation has exhibited promise in mitigating the local effects induced by Bothrops snakebite envenoming; however, the mechanisms underlying this protection are not yet fully understood. Herein, the effectiveness of photobiomodulation effects on regenerative response of C2C12 myoblast cells following exposure to Bothrops jararacussu venom (BjsuV), as well as the mechanisms involved was investigated.

Document Type

Article

Document version

Published version

Language

English

Subject (CDU)

61 - Medical sciences

Keywords

Serps -- Verí

Cèl·lules

Fotobiomodulació

Pages

15 p.

Publisher

Public Library of Science

Citation

Silva LMG, Gouveia VA, Campos GRS, Dale CS, da Palma RK, de Oliveira APL, et al. (2024) Photobiomodulation mitigates Bothrops jararacussu venom-induced damage in myoblast cells by enhancing myogenic factors and reducing cytokine production. PLoS Negl Trop Dis 18(5): e0012227. https://doi.org/10.1371/journal. pntd.0012227

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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/