Visualitzant per matèria "Antidepressius"

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Astrocyte control of glutamatergic activity: Downstream effects on serotonergic function and emotional behavior

Fullana, Neus; Gasull-Camós, Júlia; Tarrés-Gatius, Mireia; Castañé Forn, Anna; Bortolozzi, Analía; Artigas, Francesc (2020)

Major depressive disorder (MDD) is a leading cause of disability worldwide, with a poorly known pathophysiology and sub-optimal treatment, based on serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitors. ...
Involvement of NMDA receptors containing the GluN2C subunit in the psychotomimetic and antidepressant-like effects of ketamine

Tarrés-Gatius, Mireia; Miquel-Rio, Lluís; Campa, Liticia; Artigas, Francesc; Castañé Forn, Anna (2020)

Acute ketamine administration evokes rapid and sustained antidepressant effects in treatment-resistant patients. However, ketamine also produces transient perceptual disturbances similarly to those ...