Visualitzant per matèria "Expressió gènica"
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A pilot study on extracellular vesicles (EV)s and their small RNA (sRNA) expression pattern in Huntington's Disease progression
(2021-09-15)The characterization of the small transcriptome reveals a generalized down-regulation both at premanifest and manifest stages, which brings out the course of Huntington’s disease. Partial Least Squares ... -
Cell compartment isoform expression analysis using long-read transcriptomics
(2023-09-01)Motivation: Alternative splicing, a crucial post-transcriptional process, enhances proteomic diversity without increasing gene numbers, playing pivotal roles in gene regulation, specialization, and ... -
Development of a scoring function for finding differential expression - application to Lolium Perenne
(2017-09)RNA-sequencing for detecting changes between expression patterns has emerged as a frequent tool in life sciences stud- ies. However, it is an under-development tool which still lacks a standard ... -
Estudi de mètodes de deconvolució
(2023-01-30)La Deconvolució és una eina computacional que permet identificar i quantificar els tipus cel·lulars presents en una matriu d’expressió d'una mostra bulk o mixta. Actualment, aquesta tècnica es pot dur ... -
Interferon-stimulated gene expression in HIV-1 inoculated macrophages and healthy Langerhans cells: The impact of macrophage polarization and Langerhans cell maturation
(2024-09-30)Abstract Background: Antigen presenting cells (APCs) have been extensively studied for their role in human immunodeficiency virus type 1 (HIV-1) infection. HIV-1 is readily recognized by APCs, which ... -
Novel transcript discovery in yeast using sequencing reads from Oxford Nanopore Technologies in comparison to Next Generation Sequencing
(2018-09)The advent of Oxford Nanopore Technologies is expected to play a pivotal role in near future sequencing studies. Omics data analysis and related processes, currently bound to Next Generation Sequencing, ... -
Rna sequencing role in the genetic diagnosis of hereditary breast and ovarian cancer
(2024-09-10)Hereditary breast and ovarian cancer (HBOC) is a syndrome defined by an increased risk of developing breast cancer (BC) and/or ovarian cancer (OC), mainly due to germline pathogenic variants in BRCA1 ...