Visualitzant per matèria "Genomes"
Ara mostrant els elements 1-6 de 6
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Computational toolbox towards evolutionary domain mapping of membrane proteins
(2014-01)Membrane proteins account for about 20% to 30% of all proteins encoded in a typical genome. They play central roles in multiple cellular processes mediating the interaction of the cell with its ... -
Finding and characterizing Partially Methylated Domains in human haematopoietic cells
(2014-09)DNA cytosine methylation has been demonstrated to be a central epigenetic modification that has essential roles in a myriad of cellular processes. Some examples of these include gene regulation, DNA-protein ... -
Genome-wide DNA methylation association study of predominant breastfeeding
(2016-09-19)Introduction: Breastfeeding is considered a healthy habit with clear benefits at population level. It has been associated with lower risk of infections, asthma, obesity, diabetes or malocclusion, with ... -
Polygenic Risk Score in complex diseases
(2018-09)Motivation: Plenty genome-wide datasets are produced from complex diseases by traditional GWAS studies, but they are limited. A new approach has emerged in the last decade, the Polygenic Risk Scores ... -
Refining and improving a next-generation sequencing gene panel for clinical diagnosis of hereditary hematologic diseases and development of bioinformatic tools for biomedical analysis
(2019-11-12)En este doctorado industrial, el objetivo era cumplir los objetivos innovadores de Whole Genix, que incluyen: dominar los protocolos de secuenciación masiva de próxima generación (en inglés next-generation ... -
Whole Genome Prediction of Bladder Cancer Risk With the Bayesian LASSO
(2014)To build a predictive model for urothelial carcinoma of the bladder (UCB) risk combining both genomic and nongenomic data, 1,127 cases and 1,090 controls from the Spanish Bladder Cancer/EPICURO study ...