Visualitzant per matèria "Proteïnes de membrana"
Ara mostrant els elements 1-9 de 9
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Anàlisi de les interfícies d’interacció en homòmers de receptors acoblat a proteïna G
(2017-06)Els receptors acoblats a proteïna G (GPCRs en l’acrònim en anglès) formen la família més gran de proteïnes de membrana. Estan involucrats en importants funcions fisiològiques i constitueixen dianes ... -
Bioinformatics tools for membrane proteins: from sequences to structure and function
(2022-02-09)Membrane proteins are a large group of proteins that play an essential role in the cell. This group includes receptors, ion channels, transporters, and enzymes, which account for 25% of the proteins in ... -
Computational toolbox towards evolutionary domain mapping of membrane proteins
(2014-01)Membrane proteins account for about 20% to 30% of all proteins encoded in a typical genome. They play central roles in multiple cellular processes mediating the interaction of the cell with its ... -
Development of an isothermal proteome integral solubility alteration assay to identify novel membrane protein targets, preliminary studies
(2022-06)Al llarg de la vida, estem exposats a diversos compostos químics que estan presents en l’aire, aigua, o en els aliments. Aquests compostos poden interactuar amb la cèl·lula mitjançant les proteïnes ... -
Generation of a cellular model, based on CaCO2 cells, to study tight junction's formation and dynamics. CRISPR/Cas mediated gene edition to fluorescently tag the occludin protein
(2020-06)Tight junctions are present in all epithelial tissues and are involved in several processes of signalling and barrier formation. Although the proteins that compose them are known, some of the exact ... -
Influence of the g conformation of Ser and Thr on the structure of transmembrane helices
(2010)In order to study the influence of Ser and Thr on the structure of transmembrane helices we have analyzed a database of helix stretches extracted from crystal structures of membrane proteins and an ... -
Pathogenicity of homologous mutations in membrane proteins
(2022-06)Les variacions en les proteïnes de membrana poden conduir a conseqüències patògenes o no patògenes. És de vital rellevància estudiar aquelles variacions que poden acabar donant patogenicitat, per tal ... -
Prediction and punctuation of the effect of non-synonymous single nucleotide polymorphisms of the structure and function of membrane proteins
(2016-09)In recent years many SNPs have been identified, some of these linked to certain diseases and other with unknown effects. Different web servers have been developed to classify SNP in pathological or not ... -
TMalphaDB and TMbetaDB: web servers to study the structural role of sequence motifs in α-helix and β-barrel domains of membrane proteins
(2015)Background Membrane proteins represent over 25 % of human protein genes and account for more than 60 % of drug targets due to their accessibility from the extracellular environment. The increasing ...