Listando por materia "Càncer"
Mostrando ítems 1-20 de 23
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A dynamic model for the risk of bladder cancer progression
(2012)We propose a multistate modeling approach to describe the observed evolution of patients diagnosed with nonmuscle- invasive bladder cancer. On the basis of data from the Spanish Bladder Cancer/EPICURO ... -
A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm)
(2016)Pancreatic ductal adenocarcinoma (PDAC) is the most representative form of pancreatic cancers. PDAC solid tumours are constituted of heterogeneous populations of cells including cancer stem cells (CSCs), ... -
An unsupervised multi-omics clustering based on ensemble deep learning reveals subgroups of cancer patients
(2021-09)ancer is a complex disease caused by the abnormal behavior and interaction of different bio entities (e.g., genes, proteins and epigenetic factors), which are profiled using omics technologies (e.g., ... -
Anàlisi de l'impacte del càncer a partir d'un registre de tumors
(2024-05-09)La informació clínica i epidemiològica sobre el càncer interessa per descriure’n la seva etiologia, per assolir el diagnòstic de certesa i per millorar la supervivència dels malalts perquè els metges, ... -
Application of Multi-SNP Approaches Bayesian LASSO and AUC-RF to Detect Main Effects of Inflammatory-Gene Variants Associated with Bladder Cancer Risk
(2013)The relationship between inflammation and cancer is well established in several tumor types, including bladder cancer. We performed an association study between 886 inflammatory-gene variants and bladder ... -
Association between polymorphic inversions and miRNA in cancer data
(2016-09)Inversion polymorphisms is a mechanism that involves a change in the orientation of a DNA segment within a chromosome, but there is still a lack of their association with disease. However, recently ... -
Chromatin-Bound IkBa Regulates a Subset of Polycomb Target Genes in Differentiation and Cancer
(2013)IkB proteins are the primary inhibitors of NF-kB. Here, we demonstrate that sumoylated and phosphorylated IkBa accumulates in the nucleus of keratinocytes and interacts with histones H2A and H4 at the ... -
La cicatriz (in)visible La representación del cuerpo en blogs de mujeres con cáncer de mama
(2015)En este artículo analizamos la representación del cuerpo en blogs de mujeres con cáncer de mama. Fijándonos tanto en los textos como en las imágenes, estudiamos la representación del cuerpo a partir ... -
Compartir la enfermedad on-line: Narrativas de restitución y búsqueda en blogs de mujeres con cáncer de mama
(2015)Este artículo analiza 7 blogs de mujeres con cáncer de mama con el fin de observar qué narrativas de la enfermedad (Frank, 1995) predominan en sus textos e imágenes. La narrativa más presente es la ... -
Current developments in gastric cancer: from molecular profiling to treatment strategy
(2023)Gastric cancer and gastro-oesophageal junction cancer represent a global health-care challenge. Despite the efficacy of improved chemotherapy and surgical options, these patients still have a ... -
Disseny d’inhibidors de la proteïna TKTL1 mitjançant tècniques de Modelització molecular
(2018-06)La transketolase (TKT) és un homodímer amb dos centres actius de difosfat de tiamina (ThDP) situats a la interfície entre els dos monòmers juntament amb els seus cations bivalents corresponents, els ... -
Guidelines for specialized nutritional and metabolic support in the critically-ill patient. Update. Consensus SEMICYUC-SENPE: Oncohematological patient
(2011)Patients with cancer, irrespective of the stage of their disease, can require admission to the intensive care unit as a result of the complications of their underlying process or the surgical or ... -
Gut health impact in breast cancer: exploring diet, prebiotics and probiotics for enhanced treatment outcomes in women
(2024-04)This systematic review investigates the influence of diet and supplementation with prebiotics and probiotics on the composition and diversity of the gut microbiota in women (+18) diagnosed with breast ... -
Implementació d'un model de Machine Learning per la predicció del receptor d'estrogen en el càncer de mama
(2022-06)El càncer de mama és la neoplàsia maligna més freqüent entre les dones, i ocupa la primera posició pel que fa a mortalitat respecte als altres tipus de càncers. Per reduir els índexs de mortalitat, és ... -
«Me quedaré con lo positivo»: Análisis de blogs de mujeres con cáncer de mama
(2014)En este artículo se analizan siete blogs escritos por mujeres con cáncer de mama. En primer lugar, se indaga sobre su forma de concebir el cuerpo en relación, por un lado, al impacto del cáncer en los ... -
Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA-methyltransferase inhibitors
(2014)BACKGROUND AND PURPOSE Inhibitors of DNA methyltransferases (DNMTs), such as azacytidine, decitabine and zebularine, are used for the epigenetic treatment of cancer. Their action may depend upon their ... -
Reverse of Epithelial to Mesenchymal Transition by anti-AKT2 siRNA delivered by Nanoparticles
(2014-06-19)Epithelial to Mesenchymal Transition (EMT) is mechanism involved in tumor progression and dissemination, with great potential for development of new targeted anti-cancer therapies. In this Final Degree ... -
Risk Prediction Scores for Recurrence and Progression of Non-Muscle Invasive Bladder Cancer: An International Validation in Primary Tumours
(2014)Abstract Objective: We aimed to determine the validity of two risk scores for patients with non-muscle invasive bladder cancer in different European settings, in patients with primary tumours. Methods: ... -
Role of semaphorins, neuropilins and plexins in cancer progression
(2024)Progress in understanding nervous system-cancer interconnections has emphasized the functional role of semaphorins (SEMAs) and their receptors, neuropilins (NRPs) and plexins (PLXNs), in cancer progression. ...