Listando por materia "Dinàmica molecular"
Mostrando ítems 1-4 de 4
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Computational exploration of the binding mode of heme-dependent stimulators into the active catalytic domain of soluble guanylate cyclase.
(2016-10)Soluble guanylate cyclase (sGC), the main target of nitric oxide (NO), has been proven to have a significant role in coronary artery disease, pulmonary hypertension, erectile dysfunction, and myocardial ... -
Disseny d’inhibidors de la proteïna TKTL1 mitjançant tècniques de Modelització molecular
(2018-06)La transketolase (TKT) és un homodímer amb dos centres actius de difosfat de tiamina (ThDP) situats a la interfície entre els dos monòmers juntament amb els seus cations bivalents corresponents, els ... -
Influence of the g conformation of Ser and Thr on the structure of transmembrane helices
(2010)In order to study the influence of Ser and Thr on the structure of transmembrane helices we have analyzed a database of helix stretches extracted from crystal structures of membrane proteins and an ... -
Modelling GPCR homodimers using molecular dynamics simulations
(2018-09-17)G protein-coupled receptors (GPCRs) form the largest family of membrane proteins in the human genome and are involved in important physiological functions. Therefore, they are very attractive pharmacological ...