Listando por materia "Genètica"
Mostrando ítems 1-16 de 16
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Application of Multi-SNP Approaches Bayesian LASSO and AUC-RF to Detect Main Effects of Inflammatory-Gene Variants Associated with Bladder Cancer Risk
(2013)The relationship between inflammation and cancer is well established in several tumor types, including bladder cancer. We performed an association study between 886 inflammatory-gene variants and bladder ... -
AUC-RF: A New Strategy for Genomic Profiling with Random Forest
(2011)Objective: Genomic profiling, the use of genetic variants at multiple loci simultaneously for the prediction of disease risk, requires the selection of a set of genetic variants that best predicts ... -
Caracterització funcional de les causes genètiques de pacients amb malalties metabòliques hereditàries i Parkinson
(2018-06-15)El diagnòstic de malalties minoritàries (MM) denominades rares, tals com són les malalties metabòliques hereditàries, és un procés complex que implica una acurada caracterització clínica i bioquímica ... -
Del model d'hiperespecialització funcional al model de xarxa: connectoma
(2022-05)L’avenç tecnològic de les tècniques de registre “in viu” de senyals i imatges, l’aparició de nous models d’interpretació de dades, com també els resultats de les investigacions i estudis del SNC sobre ... -
Dissecting the genetic signatures of a multipotent hematopoietic progenitor’s subpopulations
(2017-09-12)In hematopoiesis and other developmental systems, there is an active debate regarding the heterogeneity of apparently phenotypically homogeneous progenitors having different lineage potentials. The ... -
Functional study of genetic variants in TRPA1 identified in patients with Small Fiber Neuropathy associated with chronic pain
(2024-06)This project aims to functionally characterize genetic variants of the TRPA1 ion channel identified in patients with idiopathic small fiber neuropathy (iSFN), a condition often associated with chronic ... -
Gene Ontology Function prediction in Mollicutes using Protein-Protein Association Networks
(2011)Abstract Background: Many complex systems can be represented and analysed as networks. The recent availability of large-scale datasets, has made it possible to elucidate some of the organisational ... -
Gene Set Analysis for improving genetic association studies
(2014-01)Introduction. Genetic epidemiology is focused on the study of the genetic causes that determine health and diseases in populations. To achieve this goal a common strategy is to explore differences in ... -
Genes candidatos al futuro desarrollo de dislexia relacionados con el sistema auditivo
(2021-06)El desarrollo del lenguaje es fundamental en el individuo para poder comunicarse e interaccionar durante la vida adulta. El desarrollo de éste es crucial durante los primeros los primeros años de ... -
Genetic analysis of the anticoagulant proteins Antithrombin, Protein C and Protein S
(2020-09-15)Cardiovascular diseases (CVDs) are the number one case of dead globally according to the World Health Organisation (WHO) ahead of cancer and respiratory diseases. Most of CVDs are caused by a combination ... -
Improving strategies for detecting genetic patterns of disease susceptibility in association studies
(2008)The analysis of gene interactions and epistatic patterns of susceptibility is especially important for investigating complex diseases such as cancer characterized by the joint action of several genes. ... -
Integrative analysis of the Regulatory Region of the FGFR3 Oncogene
(2011)The study of transcriptional regulation often needs the integration of diverse yet independent data. In the present work, sequence conservation, predic-tion of transcription factor binding sites (TFBS) ... -
Investigating the Genetic Basis of the Co-occurrence of Irritable Bowel Syndrome and Anxiety
(2021-09-13)Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder representing a serious burden to the healthcare system. IBS research is extremely challenging due to the multifactorial etiology ... -
mbmdr: an R package for exploring gene–gene interactions associated with binary or quantitative traits
(2010)Summary: We describe mbmdr, an R package for implementing the model-based multifactor dimensionality reduction (MB-MDR) method. MB-MDR has been proposed by Calle et al. as a dimension reduction method ... -
Proposal, evaluation and application of two new methodologies for genetic profiling in association studies
(2015-04-22)L'objectiu de l'epidemiologia genètica és comprendre els efectes dels gens i els factors ambientals en la salut humana. Un aspecte important és l’estudi del paper de la variabilitat genètica en el risc ...