Browsing by Subject "Antígens HLA"

Now showing items 1-2 of 2

A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques

Mothe, B.; Hu, Xintao; Llano, Anuska; Rosati, Margherita; Olvera, Alex; Kulkarni, Viraj; Valentin, Antonio; Alicea, Candido; Pilkington, Guy R.; Sardesai, Niranjan J.; Rocafort, Muntsa; Crespo, Manel; Carrillo, Jorge; Marco, Andrés; Mullins, James I.; Dorrell, Lucy; Hanke, Thomas; Clotet, Bonaventura; Pavlakis, George N.; Felber, Barbara; Brander, Christian (2015)

Background: None of the HIV T-cell vaccine candidates that have reached advanced clinical testing have been able to induce protective T cell immunity. A major reason for these failures may have been ...
The HLA-C*04:01/KIR2DS4 gene combination and human leukocyte antigen alleles with high population frequency drive rate of HIV disease progression

Olvera, Alex; Pérez-Alvarez, Susana; Ibarrondo, Javier; Ganoza, C.; Lama, Javier R.; Lucchetti, Aldo; Cate, Steven; Hildebrand, William; Bernard, Nicole; Gómez, Guadalupe; Sanchez, Jorge; Brander, Christian (2015)

Objective: The objective of this study is to identify human leukocyte antigen (HLA) class I and killer-cell immunoglobulin-like receptor (KIR) genotypes associated with different risks for HIV acquisition ...