Listando por materia "Genètica humana"
Mostrando ítems 1-10 de 10
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A population genomic analysis of genetic markers associated to Twinning susceptibility in humans
(2018-09-17)Spontaneous dizygotic (DZ) twinning is a complex trait with an important contribution from environmental factors and genetic disposition. Twin births is a common event with a worldwide incidence that ... -
Chromatin-Bound IkBa Regulates a Subset of Polycomb Target Genes in Differentiation and Cancer
(2013)IkB proteins are the primary inhibitors of NF-kB. Here, we demonstrate that sumoylated and phosphorylated IkBa accumulates in the nucleus of keratinocytes and interacts with histones H2A and H4 at the ... -
Defective signaling through plexin-A1 compromises the development of the peripheral olfactory system and neuroendocrine reproductive axis in mice
(2017)The olfacto-genital syndrome (Kallmann syndrome) associates congenital hypogonadism due to gonadotropin-releasing hormone (GnRH) deficiency and anosmia. This is a genetically heterogeneous developmental ... -
Evolutionary analyses of gene by environment variants associated to body shape in human populations
(2016-09-19)Obesity and body fat distribution is a complex phenotype highly heritable. Genetic variants showing association with BMI, a measure of body size, or waist-to-hip ratio adjusted for BMI (WHRadjBMI ), ... -
Gene Promoter Evolution Targets the Center of the Human Protein Interaction Network
(2010)Assessing the contribution of promoters and coding sequences to gene evolution is an important step toward discovering the major genetic determinants of human evolution. Many specific examples have ... -
Genomas y proteomas
(2000)Una lección como la que hoy tengo el placer de leer con motivo del acto inaugural del curso 2000-2001 tiene que tener forzosamente unas características algo diferentes de las lecciones que impartimos ... -
Genomes i proteomes
(2000)Una lliçó com la que avui tinc el gust de llegir amb motiu de l'acte inaugural del curs 2000-2001 ha de tenir forçosament unes característiques una mica diferents de les lliçons que impartim al llarg ... -
Reciprocal Translocations in Cattle: frequency estimation
(2010)Chromosomal anomalies, like Robertsonian and reciprocal translocations represent a big problem in cattle breeding as their presence induces, in the carrier subjects, a well documented fertility ... -
The role of genetic ancestry in Alzheimer’s disease: Comparative methodology, framework development and genome-wide association analysis
(2024-09-10)Understanding the role of genetic ancestry in Alzheimer's disease (AD) is crucial for uncovering the complexities of this neurodegenerative disorder. While most studies account for global ancestry, ... -
Topological Mapping of genetic variations in human Olfactory Receptors
(2018-09-17)The human olfactory system has enormous discriminatory power, with the ability to detect millions of different odorants. The initial recognition of chemical volatiles is performed by the large family of ...