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Browsing by Subject "Immunogenètica"

Now showing items 1-3 of 3

    • A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques 

      Mothe, B.; Hu, Xintao; Llano, Anuska; Rosati, Margherita; Olvera, Alex; Kulkarni, Viraj; Valentin, Antonio; Alicea, Candido; Pilkington, Guy R.; Sardesai, Niranjan J.; Rocafort, Muntsa; Crespo, Manel; Carrillo, Jorge; Marco, Andrés; Mullins, James I.; Dorrell, Lucy; Hanke, Thomas; Clotet, Bonaventura; Pavlakis, George N.; Felber, Barbara; Brander, Christian (2015)
      Background: None of the HIV T-cell vaccine candidates that have reached advanced clinical testing have been able to induce protective T cell immunity. A major reason for these failures may have been ...

    • An evaluation of automated methods for cell type annotation in scRNA-seq data 

      Costa Garrido, Anna (2022-09)
      Single-cell RNA sequencing (scRNA-seq) is a powerful new method that makes it possible to study gene expression data at the level of individual cells. Cell type annotation, using a reference sets, is ...

    • Determination of immunogenic epitopes 

      Farriol Duran, Roc (2020-09-15)
      The identification of immunogenic epitopes (such as fragments of proteins, in particular peptides, that can trigger an immune response) is a fundamental need for immune-based therapies. A computational ...