Visualitzant per matèria "Proteïnes -- Investigació"
Ara mostrant els elements 1-7 de 7
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Codon frequency is modulated by proteic selection, resulting in a coding profile in Archaea and Yeast
(2021-08)Codons as fragments of the genetic code articulate both nucleotidic and proteic constraints. If codon usage bias is now admitted to be mainly influenced by GC content, codon frequencies in general may ... -
Development of E3-Independent protac molecules
(2020-06)This project proposes to generate a new type of PROTAC molecules that can act independently of E3-ubiquitin ligases. The idea is to bind a target protein, which we want to degrade, directly to the ... -
Genetic analysis of the anticoagulant proteins Antithrombin, Protein C and Protein S
(2020-09-15)Cardiovascular diseases (CVDs) are the number one case of dead globally according to the World Health Organisation (WHO) ahead of cancer and respiratory diseases. Most of CVDs are caused by a combination ... -
HRAS physical feature analysis: Predicting protein activation through a random forest classifier
(2023-09-10)Over the past decade, increased computational capabilities have enabled us to address biological questions using data-driven methods, particularly where traditional techniques have been limiting. We ... -
Initial exploration of vascular endothelial growth factor effect on fibroblasts in the context of wound healing
(2020-06)Fibroblasts are key elements on the wound healing process, to close the wound they must migrate, migration is mediated by transmembrane proteins called integrins, especially by integrin α5β1. Anomalous ... -
Paper de les Galectines en l'impacte de les LDL agregades a les vies de senyalització del receptor LRP1
(2019-06)L'aterosclerosi engloba diversos processos patològics caracteritzats pel remodelat i l'engruiximent de les parets arterials que acaben perdent la seva elasticitat. L’aterosclerosi es produeix degut a ... -
The impact and function of C-terminal degrons and protein misfolding in the degradation of truncated proteins
(2020-09-15)Premature Termination Codons (PTCs) are mainly generated after nonsense and frameshift alterations. The Nonsense Mediated Decay (NMD) system detects and degrades mRNAs containing PTCs. However, the ...