Association between polymorphic inversions and miRNA in cancer data
| dc.contributor | Universitat de Vic - Universitat Central de Catalunya. Facultat de Ciències i Tecnologia | |
| dc.contributor | Universitat de Vic - Universitat Central de Catalunya. Màster Universitari en Anàlisi de Dades Òmiques | |
| dc.contributor.author | Ramírez Priego, Patrícia | |
| dc.date.accessioned | 2019-02-07T17:06:16Z | |
| dc.date.available | 2019-02-07T17:06:16Z | |
| dc.date.created | 2016-09 | |
| dc.date.issued | 2016-09 | |
| dc.identifier.uri | http://hdl.handle.net/10854/5677 | |
| dc.description | Curs 2015-2016 | |
| dc.description.abstract | Inversion polymorphisms is a mechanism that involves a change in the orientation of a DNA segment within a chromosome, but there is still a lack of their association with disease. However, recently developed computational methods have enabled to discover new human inversion polymorphisms and their association with complex diseases. To overcome this lack of knowledge, we aimed to investigate the effect of four well characterized inversions (8p23, 15q24.2, 16p11.2 and 17q23.31) on miRNA expression in cancer samples. We perform an association analysis between inversion and miRNA expression and Gene Ontology enrichment analysis using different R packages. Our preliminary findings show that there are an association between miRNA expression and cancer, and that it affects important pathways related to cancer. | es |
| dc.format | application/pdf | es |
| dc.format.extent | 54 p. | es |
| dc.language.iso | eng | es |
| dc.rights | Aquest document està subjecte a aquesta llicència Creative Commons | es |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/es/ | es |
| dc.subject.other | Bioinformàtica | es |
| dc.subject.other | Càncer | es |
| dc.subject.other | ADN | es |
| dc.title | Association between polymorphic inversions and miRNA in cancer data | es |
| dc.type | info:eu-repo/semantics/masterThesis | es |
| dc.description.version | Director/a: Juan Ramón González Co-director/a: Josep Maria Jurado | |
| dc.description.version | Supervisor: | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
Files in this item
This item appears in the following Collection(s)
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0/es/
