Treballs de Fi de Màster: Recent submissions
Now showing items 81-100 of 641
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Cell compartment isoform expression analysis using long-read transcriptomics
(2023-09-01)Motivation: Alternative splicing, a crucial post-transcriptional process, enhances proteomic diversity without increasing gene numbers, playing pivotal roles in gene regulation, specialization, and ... -
Host epigenetic changes to Salmonella Paratyphi exposure
(2023-09-10)Motivation: Typhoid fever, resulting from Salmonella enterica serovars Typhi and Paratyphi A, stands as a significant contributor to illness and mortality. Recent challenge studies on the host immunity ... -
Unveiling distinct features of long-term benefit in metastatic NSCLC patients undergoing immune checkpoint blockade
(2023-09-01)Introduction: Immunotherapy is firmly established as a treatment regimen in various solid tumors, driven by its exceptional benefits observed in a select group of patients. Despite widespread use of ... -
Transcriptomic analysis of BRCA1 and BRCA2 carriers
(2023-09-01)Most frequently mutations that lead to the development of breast and ovarian cancer are BRCA1 and BRCA2. Blood samples from BRCA1, BRCA2 and non-mutation carriers were extracted for both healthy and ... -
Lipid metabolism as a therapeutic vulnerability in medulloblastoma
(2023-09-01)Medulloblastoma (MB) is the most common malignant brain tumor in children and presents a varied prognosis, with some patients succumbing to the disease and survivors presenting neurotoxic sequelae from ... -
HRAS physical feature analysis: Predicting protein activation through a random forest classifier
(2023-09-10)Over the past decade, increased computational capabilities have enabled us to address biological questions using data-driven methods, particularly where traditional techniques have been limiting. We ... -
A CITE-seq analytical pipeline for the identification and molecular characterisation of dual targeting CAR T-cell products
(2023-09-01)The clinical application of T-cells genetically engineered to express a chimeric antigen receptor (CAR) targeting CD19 is challenged by CD19 negative relapse in B-cell acute lymphoblastic leukaemia (B-ALL). ... -
Benchmark of different library-free DIA strategies
(2023-09-10)Abstract Motivation: Proteomics is advancing rapidly and testing and comparing recently published mass spectrometry acquisition and data analysis methods is the best way to keep up with the advances as ... -
Machine learning-based gene expression signature for classification of endocrine therapy sensitivity in ER+ breast cancer patients
(2023-09-10)Abstract: Endocrine therapy (ET) combined with cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) is the standard treatment for metastatic estrogen receptor-positive (ER+) breast cancer. However, not all ... -
Employing serial Cox modeling for identification of pan-cancer biphasic genes
(2023-09-10)Abstract Motivation: Some genes, termed 'biphasic genes', can transition between a preventive and promoting effect on disease recurrence during cancer progression. Identifying these genes poses substantial ... -
Deep learning for oncological medical image
(2023-09-10)Abstract Background: The emergence of deep learning (DL) in the field of medical imaging has brought significant improvements, especially in pathology and radiology. In pathology, artificial intelligence ... -
Understanding the effect of ivermectin in non-severe COVID-19 patients through transcriptomics analyses
(2023-09-10)Abstract Motivation: Ivermectin inhibits SARS-CoV-2 replication in vitro at concentrations 35 times higher than approved clinical dosages for humans. This finding prompted numerous randomized clinical ... -
Establishing bioinformatic benchmarks for in vitro engineered thymus from human pluripotent stem cells
(2023-09-01)Advancements in regenerative medicine have facilitated the development of fully human artificial thymic organoids (ATO) derived from human pluripotent stem cells (hPSCs) in vitro. This study presents a ... -
It is possible to extrapolate pathogenicity in mutations in the same position in homologous proteins
(2023-09-10)Abstract When we compare an individual’s genome with the reference, several mutations are encountered. Most of these mutations are neutral, but some others can lead to pathogenic consequences. Given ... -
La educación inclusiva musical en la comarca de Osona
(2023-09-01)El presente estudio tiene como objetivo principal analizar el grado de inclusión de las clases de música de primaria en la comarca de Osona, a través de la evaluación de las actitudes, conocimientos y ... -
‘Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis': traducción de un artículo científico especializado
(2023-08-31)El objetivo del presente trabajo es definir y descubrir las principales características de la traducción científica. Para ello, en primer lugar, se ha llevado a cabo una aproximación teórica al concepto ... -
Educación inclusiva, democrática e interculturalidad crítica. Una revisión de la literatura en Latinoamérica
(2023-09-01)Los sistemas educativos se han transformado respondiendo a los cambios sociales de cada época. Desde la Declaración de los Derechos Humanos hace siete décadas, hasta llegar el surgimiento en las últimas ... -
Las claves del asesoramiento psicopedagógico. Revisión bibliográfica
(2023-09-01)El estudio se basa en una revisión bibliográfica de artículos relevantes de los últimos 5 años para abordar la investigación de factores clave para el asesoramiento psicopedagógico colaborativo efectivo ... -
La productividad de la traducción asistida y automática en los textos del área estadística: una evaluación de la traducción del inglés al español
(2023-09-06)El presente trabajo de investigación tiene como objetivo evaluar la productividad de la posedición traducción asistida y la traducción automática del inglés al español de textos de estadística. Se realizó ... -
Análisis contrastivo del testamento español y suizo francés: traducción jurídica y comentario traductológico
(2023-09-06)Los movimientos migratorios existen desde los inicios de la especie humana, motivados por la búsqueda de una mejor vida u obligados por la situación político-económica de un país. Así, España perdió, ...